[Obstetrical complications and further schizophrenia of the infant: a new medicolegal threat to the obstetrician?].
Identifieur interne : 000310 ( France/Analysis ); précédent : 000309; suivant : 000311[Obstetrical complications and further schizophrenia of the infant: a new medicolegal threat to the obstetrician?].
Auteurs : G. Boog [France]Source :
- Journal de gynecologie, obstetrique et biologie de la reproduction [ 0368-2315 ] ; 2003.
Descripteurs français
- KwdFr :
- Complications de la grossesse (physiopathologie), Complications de la grossesse (psychologie), Complications du travail et de l'accouchement (physiopathologie), Complications du travail et de l'accouchement (psychologie), Effets différés de l'exposition prénatale aux facteurs de risque, Encéphale (malformations), Facteurs de risque, Femelle, Grossesse, Hormones (effets indésirables), Hormones (usage thérapeutique), Humains, Maladies virales (), Mères, Nouveau-né, Phénomènes physiologiques nutritionnels prénatals, Poids de naissance, Schizophrénie (épidémiologie), Schizophrénie (étiologie), Stress psychologique (), Travail obstétrical (psychologie).
- MESH :
- effets indésirables : Hormones.
- malformations : Encéphale.
- physiopathologie : Complications de la grossesse, Complications du travail et de l'accouchement.
- psychologie : Complications de la grossesse, Complications du travail et de l'accouchement, Travail obstétrical.
- usage thérapeutique : Hormones.
- épidémiologie : Schizophrénie.
- étiologie : Schizophrénie.
- Effets différés de l'exposition prénatale aux facteurs de risque, Facteurs de risque, Femelle, Grossesse, Humains, Maladies virales, Mères, Nouveau-né, Phénomènes physiologiques nutritionnels prénatals, Poids de naissance, Stress psychologique.
English descriptors
- KwdEn :
- Birth Weight, Brain (abnormalities), Female, Hormones (adverse effects), Hormones (therapeutic use), Humans, Infant, Newborn, Labor, Obstetric (psychology), Mothers, Obstetric Labor Complications (physiopathology), Obstetric Labor Complications (psychology), Pregnancy, Pregnancy Complications (physiopathology), Pregnancy Complications (psychology), Prenatal Exposure Delayed Effects, Prenatal Nutritional Physiological Phenomena, Risk Factors, Schizophrenia (epidemiology), Schizophrenia (etiology), Stress, Psychological (complications), Virus Diseases (complications).
- MESH :
- chemical , adverse effects : Hormones.
- abnormalities : Brain.
- complications : Stress, Psychological, Virus Diseases.
- epidemiology : Schizophrenia.
- etiology : Schizophrenia.
- physiopathology : Obstetric Labor Complications, Pregnancy Complications.
- psychology : Labor, Obstetric, Obstetric Labor Complications, Pregnancy Complications.
- chemical , therapeutic use : Hormones.
- Birth Weight, Female, Humans, Infant, Newborn, Mothers, Pregnancy, Prenatal Exposure Delayed Effects, Prenatal Nutritional Physiological Phenomena, Risk Factors.
Abstract
Schizophrenia is a multifactorial disease with complex interactions between a genetic liability, possible perinatal complications and exposure to later environmental risk factors in childhood. Maternal influenza infection, wartime-famine-related denutrition and maternal depression or exposure to repeated stress in pregnancy may have a deleterious effect on brain development and neuronal migration. Obstetrical complications which are significantly associated with schizophrenia are bleeding, diabetes, prematurity, fetal growth retardation, Rhesus incompatibility, preeclampsia and congenital malformations. Subjects with onset of schizophrenia before age 22 had more often a history of acute fetal distress (abnormal presentation at birth and complicated cesarean delivery). Obstetrical complications may have a direct negative impact on fetal brain development or may be on the causal pathway between prepartum maternal depression or psychosis, exposure to stress and impaired relation between mother and child consecutive to postnatal depression.
PubMed: 15067896
Affiliations:
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pubmed:15067896Le document en format XML
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<term>Hormones (therapeutic use)</term>
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<term>Stress psychologique ()</term>
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<front><div type="abstract" xml:lang="en">Schizophrenia is a multifactorial disease with complex interactions between a genetic liability, possible perinatal complications and exposure to later environmental risk factors in childhood. Maternal influenza infection, wartime-famine-related denutrition and maternal depression or exposure to repeated stress in pregnancy may have a deleterious effect on brain development and neuronal migration. Obstetrical complications which are significantly associated with schizophrenia are bleeding, diabetes, prematurity, fetal growth retardation, Rhesus incompatibility, preeclampsia and congenital malformations. Subjects with onset of schizophrenia before age 22 had more often a history of acute fetal distress (abnormal presentation at birth and complicated cesarean delivery). Obstetrical complications may have a direct negative impact on fetal brain development or may be on the causal pathway between prepartum maternal depression or psychosis, exposure to stress and impaired relation between mother and child consecutive to postnatal depression.</div>
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